Estriol 0.1% cream
Estriol 0.1% cream
Learn what Estriol is, its benefits and how to use it safely.
Medically reviewed by Dr Zahra Khan
MBBS, MSc (Dist)
Updated on 1st August 2025What is Estriol cream?
Estriol 0.1% or 1mg/g is a low-dose vaginal oestrogen cream, a body-identical form of oestrogen. It is used to treat vaginal and urinary symptoms caused by declining oestrogen levels during and after menopause.
Unlike systemic HRT, Estriol cream works by delivering oestrogen directly to the vaginal tissues with minimal absorption into the bloodstream. This makes it a trusted option for many women, including those who are not taking systemic HRT.
Why choose Estriol cream?
Estriol is a local HRT treatment for genitourinary syndrome of menopause (GSM) — symptoms affecting the vaginal and urinary areas due to low oestrogen. It is a gentle form of oestrogen suitable for long-term use.
It may be a good choice if you:
- Have vaginal dryness, itching, or soreness
- Experience pain during sex or recurrent UTIs
- Have urinary urgency or frequency
- Are not on systemic HRT but still want targeted relief
- Prefer a cream to vaginal tablets or rings
How to use Estriol
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Everything you need to know to safely use Estriol
Benefits of Estriol
With consistent use, many people notice improvement in symptoms within a few weeks, with full benefits usually seen by 2 to 3 months of regular use.
It is used to relieve a wide range of symptoms associated with low oestrogen levels in the vaginal and urinary tissues, including:
Frequently asked questions
This page is provided for reference purposes only. Always follow the advice and guidance of your prescribing doctor regarding your medication and prescriptions. Do not make any changes to your medication regimen without consulting your healthcare provider.