Evorel

Each patch delivers a steady dose of estradiol through the skin and directly into your bloodstream. This transdermal route avoids the digestive system and liver, which can reduce the risk of blood clots compared to oral oestrogen.

Evorel patches come in four strengths:

• Evorel 25 – 25 micrograms of estradiol per 24 hours
• Evorel 50
• Evorel 75
• Evorel 100

Your clinician will choose the right strength for your needs and adjust it over time if needed.

• Apply to clean, dry, hairless skin below the waist. Typically the buttocks or upper thigh. Avoid applying near the breasts or on irritated skin.
• Change the patch twice a week (e.g. every Monday and Thursday).
• Rotate the site each time to avoid skin irritation.
• Press firmly for 10–20 seconds to ensure good contact.

Most people find Evorel patches easy to tolerate. However, some may experience skin irritation where the patch is applied. When first starting HRT, it’s also common to notice mild side effects as your body adapts to the changing hormone levels. These might include breast tenderness, slight headaches, or feelings of nausea which typically resolve within a few weeks.

If symptoms continue beyond six months or become difficult to manage, it’s worth checking in with your healthcare provider. It could mean the dose or type of HRT needs adjusting. Serious risks like blood clots or breast cancer are rare, especially with transdermal oestrogen. Your personal risk will be reviewed before starting treatment.